Principal Investigator, Joshua J. Breunig, PhD is looking for a Postdoctoral Scientist to join the team!

When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters.

Neural stem cells generate the majority of the cells in the brain. The Breunig Laboratory studies the molecular mechanisms that mediate the normal differentiation of these cells to create the appropriate mature cell types in the brain, including neurons and glia (astrocytes and oligodendrocytes). Importantly, this information can be used to create therapies to direct differentiation and to promote brain repair. Conversely, we also use this knowledge to understand development of brain tumors when cells are mutated. For example, the exact origin of brain tumors is currently under debate, with most evidence pointing to either a neural stem cell origin or an oligodendrocyte progenitor origin. To learn more, please visit Breunig Research Lab | Cedars-Sinai

Are you a passionate and dedicated research professional?

As a Postdoc in Dr. Breunig's lab, working independently but in close cooperation and consultation with the Principal Investigator (PI) and other Research Scientists, you will perform routine and complex laboratory procedures throughout training period and may develop, adapt, and implement new research techniques and protocols.

Primary Duties and Responsibilities:

• May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
• May participate in publications and presentations as author or co-author.
• Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the PI.
• Analyzes, interprets, summarizes, and compiles data.
• Operates and maintains equipment and instruments.
• May observe MD-patient or MD-human research subject interactions as it pertains directly to the research being performed.
• Culturing of human iPSC lines and creation of organoids.
• Culture of mouse neural stem cells and capability to do mouse electroporation.
• Advanced molecular biology and plasmid cloning and transduction of plasmids into primary cells.
• Mentoring of graduate students and interns.
• Oversight of confocal microscope.
• Liaising with vendors to care for microscopes and training users on proper use of microscope and advice on downstream analysis.

Education:

• Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization.

Experience and Skills:

• Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
• Works independently on research projects designed by a mentor (typically the PI) within the area of specialization.
• Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis, operation and maintenance of specialized equipment.
• Excellent written and oral communication skills are essential.
• Knowledge of safety standards.
• Scheduling flexibility including evening, weekend, and holiday rotation commitment is required. Travel may be required.