The Paczesny laboratory is seeking highly motivated candidates for a post-doctoral fellowship studying tumor immunology including with hematopoietic cell transplantation to treat myeloid malignancies. The major interests of the lab are discovering and validating new biomarkers and immune cells subsets in tumor immunology, generating new cell-based immunotherapies such as T9IL33 recently published in the Journal of Experimental Medicine and highlighted in the New England Journal of Medicine, as well as developing new small molecules based on discovery of novel targets. In this position, you will have the opportunity to develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems, and primary patient samples. You will also gain extensive experience and training in proteomics, hematopoietic cell transplantation biology, and pre-clinical study development.


Job Duties:
35% - Develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel
xenograft in vivo systems, and primary patient samples. Each project leading to a presentation at a national meeting as well as
manuscript of impact factor > 6. - (Essential)

35% - Train in proteomics, hematopoietic cell transplantation biology, and pre-clinical study development. Similarly, the outcomes will
lead to a publishable manuscript - (Essential)

25% - Perform immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity
assays including for collaborative work on multi-institutional grants. - (Essential)

5% - Perform other essential duties as requested. These will include maintain animal colonies, collaborate with DLAR to provide the
best animal care, update IACUC and IBC protocols, order supplies for the laboratory. - (Essential)

Preferred Experience & Additional Skills: Successful applicants will have a Ph.D. or M.D./Ph.D. with substantial hands-on research experience in immunology; a strong publication record in recognized peer-reviewed journals; experience with multicolor flow cytometry and in immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity assays; experience with
animal models of bone marrow transplantation is required; be meticulous at planning, executing, and organizing the results for large scale assays. Must also be capable of taking initiative, work independently and in a collaborative setting. Excellent written and verbal communication skills are required, as are excellent organizational skills and knowledge of proper scientific record keeping as well as being comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.

MUSC:
The Medical University of South Carolina (MUSC) is located in the beautiful historic district of Charleston (ranked #1 travel destination in the U.S.) bounded by the Atlantic Ocean and beautiful beaches to the east, and national forests and wildlife refuges to the north and south. MUSC is the state’s top-ranked medical center. The Medical University of South Carolina is a leading medical research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future.
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations.
All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. All applicants, must also apply via MUSC online portal at:

Application materials should be addressed to the department chair:
Sophie Paczesny, MD, Ph.D.
Chair Department of Microbiology and Immunology
Medical University of South Carolina
Hollings Cancer Biology Immunology Program co-leader
Sally Abney Rose Endowed Chair in Cancer Stem Cell Biology
Basic Sciences Building, Ste 203
173 Ashley Ave, MSC 504
Charleston, SC 29425
[email protected]