Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The Arthur Riggs Diabetes & Metabolism Research Institute (AR-DMRI) promotes new discoveries and innovation across pathophysiology, diabetes-related complications, and treatment of type 1 and 2 diabetes. The long-term goal of our lab is to delineate the molecular mechanisms linking β-cell signaling to autoimmune attack in T1D. This project is focused on to determine the role of ISR signaling, dysregulated RNA transcription and translation, and neoantigen production in the β-cell during the early phases of T1D development. To achieve this goal, we have developed several molecular biology tools and high-throughput multi-omics approaches.

As a successful candidate you will:

· Independently design and carry out experiments, train graduate students and post-docs, lab management, manuscript writing, and helping the PI with grant writing, presenting data in lab meetings and national and international conferences, cordinating with collaborators and data interpretation and analysis.

· Perform necessary lab skills within cell and molecular biology to include flow cytometry, handling of laboratory animals, multi-omics, invitro transcription and translation, cell culture, immunohistochemistry, extracellular vesicles and AAV-based gene therapy, ELISPOT, CRISPR and data analysis

· The Staff Scientist must possess, at a minimum, the U.S. equivalent Bachelor’s or Master’s degree in an appropriate discipline, and will often have a Ph.D. or other doctoral level degree.

· PhD or MD with above 5 years of experience preferred

· Experience with T and B cells biology, immunotherapy, cell and molecular biology, gene and cell therapy as well as scientific writing are required

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here