Postdoctoral Fellow - Structural Biology

City of Hope

Duarte, CA

ID: 7218098 (Ref.No. 10021911)
Posted: June 17, 2024
Salary / Pay Rate: $31.00 - $34.23 / hour
Application Deadline: Open Until Filled

Job Description

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratories of Dr. Jeff Perry, a Structural Biologist, and Dr. Javier Gordon Ogembo, a Vaccinologist, are currently seeking a highly motivated and talented individual to fill a postdoctoral position in the field of gamma-herpesvirus structural biology. The goal of the postdoctoral candidate will be to elucidate the mechanisms of gamma-herpesvirus entry and contribute to vaccine development. If you are looking for a challenging and exciting opportunity to advance your research career in oncogenic gamma-herpesviruses and cancer, we invite you to join our multi-disciplinary lab. For more information about Dr. Ogembo’s lab, please visit here.

As a successful candidate, you will:

  • Access state-of-the-art facilities and resources for transitional science in a vibrant, collaborative research community.
  • Utilize FDA-approved facilities for producing investigational drugs and biologics for clinical trials.
  • Work in facilities designed to meet rigorous regulatory standards, ensuring safety and efficacy of developed products.
  • Seize the opportunity as a postdoctoral fellow to collaborate with leading experts, contributing to cutting-edge research in viral entry, oncovirology, and vaccinology.
  • Explore interactions between viruses and host cells, advancing understanding in these crucial areas.
  • Experience an exciting research environment, enhancing your career while contributing to impactful projects.

Your qualifications should include:

  • A Ph.D., Ph.D/DVM, or Ph.D/MD degree(s) in a related field and a strong background in protein biochemistry and structural biology.
  • Cell culture and aseptic technique: culture, handling, and maintenance of bacterial and mammalian cells (multiple cell lines), cryopreservation.
  • Protein production and structural assays: protein expression in different cell systems and purification; protein crystallography and/or cryo-electron microscopy; circular dichroism (CD) spectroscopy, mass spectrometry, isothermal calorimetry and/or surface plasmon resonance.
  • Immuno-assays: western blot, ELISA, flow cytometry, immunofluorescence assay, immuno-histochemistry.
  • Molecular cloning and basic DNA/RNA assays: molecular cloning, DNA/RNA isolation from cells, conventional PCR.

Preferred qualifications:

  • Experience in virology, cancer vaccines, T-cell immunology, and/or the use of animal models will be considered as a plus.
  • Virology assays: virus production and titration, virus neutralization, plaque assays.
  • Advanced DNA/RNA assays: DNA isolation from tissue, qPCR, RT-qPCR.
  • Pre-clinical animal models: animal handling (mice and/or rats), immunization, blood collection, tissue processing.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.

Salary / Pay Rate Information:
Pay Rate: $31.00 - $34.23 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.