Research Associate II

City of Hope

Duarte, CA

ID: 7214955 (Ref.No. 10024628)
Posted: February 8, 2024
Salary / Pay Rate: $32.00 - $49.60 / hour
Application Deadline: Open Until Filled

Job Description

Research Associate (Beckman Research Institute of the City of Hope; Duarte, CA): Assist in the study of preclinical antibody testing and clinical experimental therapeutics in hematologic diseases, including, but not limited to, multiple myeloma and acute myeloid leukemia using the Cytometry by Time of Flight (CyTOF) processing technique. Perform a variety of routine and non-routine laboratory research experiments and record and validate results for accuracy and completeness. Perform BioTools/Fluidigm processing using Helios Operators. Perform CyTOF Panel Design, CyTOF antibody conjugation and titration, CyTOF testing, sample acquisition, preserving, straining, processing, and data analysis. Perform single cell CyTOF software data analysis using Cytobank, FlowJo, Astrolabe, Maxpar Pathsetter and OmiqAI. Perform CyTOF maintenance and troubleshooting. Troubleshoot procedures related to mass flow cytometry, including CyTOF processing, if results are unexpected and unsatisfactory. Recommend alternative procedures related to mass flow cytometry as needed. Assist in creating, reviewing, and revising Standard Operating Procedures (SOPs) for multiple parametric flow cytometry including CyTOF testing and for running single cell mass cytometer. Contribute to the preparation of manuscripts by describing methods, including CyTOF application processing and specialized techniques. Keep abreast of new and improved techniques related to CyTOF processing. Assist in the study of the use of biomarkers and identification of novel surface receptors for multiple myeloma and leukemia patient stratification. Accurately record work performed, including results and methodology. Calculate, compile, and analyze data obtained from work performed. Independently evaluate research data and initiate alternative approaches to improve the quality of results by providing input to overall research design. Ensure that all laboratory activities are carried out in compliance with each procedure by utilizing safety procedures and guidelines in handling, storage, and disposal of bio-hazardous, infectious, and toxic material. Train lab staff in CyTOF application processing and other specialized procedures, equipment, and theoretical concepts behind unique tests.

Minimum requirements: Bachelor's degree or foreign equivalent in Biochemistry, Biological Sciences, or a related field, plus two (2) years of experience as a Research Associate or a related occupation.

Must have experience with the following: BioToolsFluidigm processing using Helios Operators; advanced single cell mass flow cytometry operation of Cytometry by Time of Flight (CyTOF) machine and subsequent data analysis; single cell CyTOF software data analysis: Cytobank, FlowJo, Astrolabe, Maxpar Pathsetter and OmiqAI; CyTOF Panel Design, CyTOF antibody conjugation and titration, CyTOF testing, sample acquisition, preserving, straining, processing, and data analysis; and CyTOF maintenance and troubleshooting.

Salary: $63,652.37 – $98,661.26 per year

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity, and inclusion, please click here.

Salary / Pay Rate Information:
Pay Rate: $32.00 - $49.60 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.