Postdoctoral Scholar- Department of Biochemistry and Molecular Biology

Job summary: Dr. Delaney, PhD, has an opening in his laboratory for a self-motivated and independent Postdoctoral Scholar.
Delaney Lab projects are centered on investigating how chromosomal copy number changes alter cell biology, particularly in the context of cancer using mice and cancer cell lines as model systems. This position requires a post-doctoral fellow to investigate metallothioneins: zinc binding proteins of relatively unknown contribution to cancer initiation and drug response. The scientific culture in the lab is to initially design projects from unbiased genome-wide assays (bioinformatic or –seq technologies) from the highest quality genetic models and work out full mechanistic stories from the outcome.

Delaney Lab projects are centered on investigating how chromosomal copy number changes alter cell biology, particularly in the context of cancer using mice and cancer cell lines as model systems. This position requires a post-doctoral fellow to investigate metallothioneins: zinc binding proteins of relatively unknown contribution to cancer initiation and drug response. The scientific culture in the lab is to initially design projects from unbiased genome-wide assays (bioinformatic or –seq technologies) from the highest quality genetic models and work out full mechanistic stories from the outcome.
The ideal candidate has previous experience in a cancer biology laboratory, however this is not required if the candidate has demonstrated productivity as evidenced by peer-reviewed publications.
Opportunities to learn and use R for bioinformatic data science are also available and encouraged. Dr. Delaney leads the Biological Big Data for Basic Scientists course at MUSC.
The ideal candidate is well-organized and able to create documentation in Word, Excel, and
Google Docs. The Postdoctoral Scholar must be able to work well in a team setting, including
the mentoring of undergraduates and colleagues. Previous experience with mice,
microscopy, metabolic assays, cell culture, and bacterial plasmid preps is desired but not
required. Previous experience with Cas9-directed mutagenesis beyond simple knockouts is
desired but not required.
The candidate must be willing to work with mice and lentivirus in an oncology context.
The candidate is expected to work hard while in the laboratory, however Dr. Delaney’s lab
culture fosters work-life balance.

Job Duties:
20% Molecular biology assays, westerns, RT-qPCR, DNA isolation, microscopy
15% Maintain mouse colony specific to project including genotyping and monitoring
15% Perform mouse experiments, including tumor cell inoculation, chemotherapeutic treatment, dissections, histology, and related molecular biology
10% Genetic manipulation of mouse and human genes using cutting-edge molecular biology techniques, DNA and RNA purification
10% Prepare cell culture samples by transfection and/or lentivirus
10% Participation in shared lab duties, i.e. reagent maintenance and inventory, general equipment/lab maintenance, data management
10% Write and submit highly competitive applications for fellowships and grants relevant to the trainee
5% Scholarly activities- including manuscript preparation, poster and oral presentations at conferences
5% Keep the lab organized and clean

For official application portal, please visit
https://musc.career-pages.com/jobs/univ-postdoctoral-scholar-department-of-biochemistry-and-molecular-biology-charleston-south-carolina-united-states-a36834d5-9ece-41f9-ac92-9b5e3a79e526

Please send CV (with 1-3 reference email contacts) and a short email containing information regarding your interest in the lab to Joe Delaney, delaneyj@musc.edu. Thank you for your interest in our research.