POSTDOCTORAL RESEASCH SCHOLAR, SYNTHETIC CHEMISTRY

Arizona State University

Tempe, AZ

ID: 7077959
Posted: May 6, 2021
Application Deadline: Open Until Filled

Job Description

Postdoctoral Research Scholar, Synthetic Chemistry
Arizona State University: Office of the Executive Vice President Knowledge Enterprise: Biodesign Institute: Biodesign BE

Location
Tempe, Arizona

Open Date
Apr 16, 2021

Description
The Arizona State University's Biodesign Center for BioEnergetics and Drs. Shengxi Chen and Sidney Hecht invite applications for a Postdoctoral Research Scholar to assist with chemical aspects of the biosynthesis of peptides and proteins containing non-proteinogenic amino acids. Specific tasks will include the design and synthesis of new amino acid analogues, the preparation of oligonucleotide derivatives of these amino acid analogues, and the purification and characterization of the peptides and proteins created in in vitro, and in vivo biochemical systems. The goal of the work includes innovations in the preparation of amino acids and activation of aminoacyl-tRNAs, and participation in understanding the effects of the newly prepared amino acids in altering peptide and protein function.

Salary Range: $52,704 - $55,000 per year; DOE

We will begin reviewing applications May 16, 2021 and will continue to review incoming applications on a biweekly basis until the position is filled. To apply for this position, candidates must submit their application through Interfolio at apply.interfolio.com/86597 (emailed applications will not be considered).

Essential Duties:

Assist with chemical aspects of the biosynthesis of peptides and proteins containing non-proteinogenic amino acids
Design and synthesis of new amino acid analogues
The preparation of oligonucleotide derivatives of these amino acid analogues.
Purification and characterization of the peptides and proteins created in in vitro, and in vivo biochemical systems.
Participation in understanding the effects of the newly prepared amino acids in altering peptide and protein function.

Qualifications
Required Qualifications:

Applicants must have a recent Ph.D (within the past four years)
Strong background in organic chemistry or a closely related field

Desired Qualifications:

Experience working with amino acids and nucleotides, or in heterocyclic chemistry.

Working Environment

Regular activities require ability to manage multiple tasks at one time, to be able to prioritize tasks; to manage conflict; to interact in a team environment; and to communicate through verbal and written work.
Activities are performed in an environmentally controlled office setting and laboratory subject to extended periods of sitting, keyboarding and manipulating a computer mouse; required to stand for varying lengths of time and walk moderate distances to perform work.
Frequent bending, reaching, lifting, pushing and pulling up to 25 pounds.
Regular activities require ability to quickly change priorities, which may include and/or are subject to resolution of conflicts.
Ability to clearly communicate verbally, read, write, see and hear to perform essential functions.
May be required to wear personal protective equipment before entering laboratories such as lab coat, gloves, safety glasses, closed toe shoes, and respirator.

Application Instructions
Applicants should submit the following materials:

Cover letter specifying relevant qualifications and training
Curriculum vitae
Statement of current research interests and expertise (2-page maximum)
Contact information for at least three professional references
At least one peer-reviewed publication.
We will begin reviewing applications May 16, 2021 and will continue to review incoming applications on a biweekly basis until the position is filled.

Department Statement:

Arizona State University is a new model for American higher education, an unprecedented combination of academic excellence, entrepreneurial energy and broad access. This New American University is a single, unified institution comprising four differentiated campuses positively impacting the economic, social, cultural and environmental health of the communities it serves. Its research is inspired by real world application blurring the boundaries that traditionally separate academic disciplines. ASU serves more than 80,000 students in metropolitan Phoenix, Arizona, the nation's fifth largest city. ASU champions intellectual and cultural diversity, and it welcomes students from all fifty states and more than one hundred nations across the globe.

For the fifth year in a row, ASU has been named the most innovative school in the nation, recognizing the university's culture of groundbreaking research and partnerships, as well as its commitment to helping students thrive in college and beyond. U.S. News and World Report has named ASU as the most innovative university all five years the category has existed.

ASU Knowledge Enterprise advances research, innovation, strategic partnerships, entrepreneurship, and international development. Our success arises from solutions-focused, interdisciplinary research; an entrepreneurial approach that is embedded in every school and department; and a commitment to transform society in a positive way. http://research.asu.edu/

The Biodesign Institute addresses today's critical global challenges in healthcare, sustainability, and security by developing solutions inspired from natural systems and translating those solutions into commercially viable products and clinical practices.

The Center for BioEnergetics, directed by Dr. Sidney Hecht, focuses on improved diagnoses and treatments for diseases caused by impaired energy metabolism. The majority of these diseases are degenerative and affect children and young adults. In addition to impacting children, impairment to the mitochondria has been implicated as a factor in aging. It is associated with Parkinson's disease, atherosclerotic heart disease, stroke, Alzheimer's disease and cancer.

Additionally, the Center is currently involved in a program involving the synthesis of proteins and peptides containing unnatural amino acid analogues. This program involves the use of modified bacterial ribosomes that we select, which are capable of introducing very unusual amino acid analogues into proteins, including D-amino acids, dipeptides and dipeptidomimetics, beta-amino acids, glycosylated amino acids and phosphorylated amino acids.

Application Process
This institution is using Interfolio's Faculty Search to conduct this search. Applicants to this position receive a free Dossier account and can send all application materials, including confidential letters of recommendation, free of charge.

Equal Employment Opportunity Statement
A background check is required for employment. Arizona State University is a VEVRAA Federal Contractor and an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other basis protected by law.

(See https://www.asu.edu/aad/manuals/acd/acd401.html and https://www.asu.edu/titleIX/.)

In compliance with federal law, ASU prepares an annual report on campus security and fire safety programs and resources. ASU’s Annual Security and Fire Safety Report is available online at https://www.asu.edu/police/PDFs/ASU-Clery-Report.pdf You may request a hard copy of the report by contacting the ASU Police Department at 480-965-3456.



 

Apply Now

Please mention to the employer that you saw this ad on UniversityJobs.com