Staff Scientist - CAR T Cell Therapeutics - Budde Laboratory

City of Hope

Duarte, CA

ID: 7066620 (Ref.No. 10005788)
Posted: May 30, 2020
Application Deadline: Open Until Filled

Job Description

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
Dr. Elizabeth Budde’s laboratory in the T Cell Therapeutics Research Laboratories (TCTRL) program is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic studies. Dr. Budde’s lab currently has an opening for a Staff Scientist.

Key Responsibilities:
  • Serve as the point of contact person for correlative studies for our CAR T cell clinical trials in acute myeloid leukemia.
  • D evelop next generation CARs for clinical translation.
  • C onduct high-dimensional analysis of patient tissues, including multi- parameter flow cytometry, immunohistochemistry and/or gene expression profiling and bioinformatics.
  • I nteract and collaborate with a team of researchers focused on developing T cell therapies in a translational research environment.

Basic education, experience and skills required for consideration:
  • Ph.D. degree with research experience in the fields of immunology, immunotherapy and cancer/acute myeloid leukemia tumor biology.
  • Ability to effectively supervise research associates and students to successfully meet project goals.
  • Ability to collaborate with diverse group of researchers involved in the correlative studies.
  • Ability to design and execute laboratory experiments, critically interpret experimental results, and present data in a clear and concise manner.
  • Ability to participate in the preparation of grant applications and scientific publications.
  • Ability to use discretionary initiative and judgment when handling confidential information.
  • Excellent communication and interpersonal skills.
  • Excellent organizational and time management skills.

Preferred Experience:
  • A publication record in peer-reviewed scientific journals.
  • Prior postdoctoral experience, with cell biology and animal work.
  • Experience with cellular therapy and/or whole genome sample preparation/analysis.
  • Ability to apply/use bioinformatics for analyses and interpretation of RNA-Seq and Single Cell RNA-Seq data is desirable.

Additional Information:
See the Elizabeth L. Budde, M.D./Ph.D. web page for an overview of research interests at: .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.


City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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