Computational Biologist

Harvard Medical School

Boston, MA

ID: 7087029
Posted: October 12, 2021
Application Deadline: Open Until Filled

Job Description

Job-Specific Responsibilities

The Jackson lab is seeking a highly motivated individual to join our team as a Computational Biologist. This individual will be mentored by Dr. Ruaidhri Jackson, an expert in mucosal immunology. The Jackson lab uses cutting edge techniques, including next-generation ribosome profiling technology, RNAseq, scRNAseq, CRISPR/Cas9 genome editing, and preclinical mouse models of disease to improve our understanding of innate and mucosal immunity. The individual will have the opportunity to participate in the analysis of both mouse and human genomic datasets, identifying novel targets and pathways for the treatment of inflammatory disease. The individual will have the opportunity to work closely with a team of experimental biologists to interpret and validate findings. The individual will join a new lab conducting cutting edge genome investigatory experiments and work closely with our lab's bioinformatic collaborators and the Harvard Chan Bioinformatic Core. Job responsibilities include:
-Employ computational and statistical tools for the analysis and interpretation of multi-modal genomic data, including bulk and single-cell RNA analyses.
-Work closely with experimental biologists to interpret and validate exciting findings and teach lab members basic bioinformatic pipelines.
-Develop novel algorithms to analyze genomic, transcriptional, and screening data sets.
-Explore novel data visualization tools, with emphasis on integrating diverse data types
-Share results and algorithms with collaborators and the global cancer and immunology research communities.
-Prepare high-quality publications and oral presentations.

Basic Qualifications

Masters degree in biological sciences or a related field required. 5+ years experience in a related area using next-gen RNAseq analysis

Additional Qualifications and Skills

Background knowledge in computational biology preferred, but most important are strong computational and quantitative skills. Strong programming skills and experience in algorithm development (using Python, R, Matlab, etc.). Coursework in Statistics, excellent oral and written English communication skills. Ability to solve complex problems. Major preference for background in ribosome profiling and mRNA splicing. Preference for experience with Illumina, Oxford Nanopore, PacBio sequencing platforms.

Additional Information

This is a one-year term position with possibility of extension, contingent on work performance and continued funding for the position.

Offer contingent on pre-placement medical evaluation.

Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.

We are committed to cultivating an inclusive workplace culture of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values

Harvard University offers an outstanding benefits package including:
Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 12.5 paid holidays, and 3 paid personal days per year.
Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
Retirement: University-funded retirement plan with full vesting after 3 years of service.
Tuition Assistance Program: Competitive tuition assistance program, incredibly affordable classes directly at the Harvard Extension School, and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation, and complementary health services.
Harvard access to athletic facilities, libraries, campus events, and many discounts throughout metro Boston.
The Harvard Medical School is not able to provide visa sponsorship for this position.

Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.